Prognostic Factors and Management of Colorectal Gastrointestinal Stromal Tumors

Abstract Introduction The gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of tract. Even though it can be found in any location digestive tract, colorectal GIST rare. With this study, we aim to review current knowledge regarding prognosis and management GIST. Methods A literature search was conducted PubMed, 717 articles were collected. After analyzing these studies, 60 selected use review. Results mitotic index, as well size identified good discriminators various studies. Surgery remains only curative therapy for potentially resectable tumors. However, even after surgical resection, some patients develop disease recurrence metastasis, especially those with high-risk Therefore, resection alone might inadequate all GISTs. discovery GIST's molecular pathway led a shift its therapy, insofar tyrosine kinase inhibitors became part treatment schemes tumor, revolutionizing treatment's outcome prognosis. Discussion/Conclusion controversy concerning be, part, attributed limited number studies literature. In review, gathered recent about rare propose two algorithms approach. Lastly, highlight importance an individualized approach setting multidisciplinary team.